铁皮石斛化学成分的研究

罗镭,祝明,陈立钻,杨兵勋,邵喜英

中国药学杂志 ›› 2013, Vol. 48 ›› Issue (19) : 1681-1683.

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中国药学杂志 ›› 2013, Vol. 48 ›› Issue (19) : 1681-1683. DOI: 10.11669/cpj.2013.19.021
论著

铁皮石斛化学成分的研究

  • 罗镭1,祝明1,陈立钻2,杨兵勋2,邵喜英3
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Chemical Constituents of Dendrobium officinale Kimura et Migo

  • LUO Lei1,ZHU Ming1,CHEN Li-zuan2,YANG Bing-xun2 ,SHAO Xi-ying3
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摘要

目的研究铁皮石斛(DendrobiumofficinaleKimuraetMigo)的化学成分。方法采用反相硅胶色谱柱色谱、聚酰胺色谱柱色谱、凝胶色谱柱色谱等方法分离化合物,运用现代光谱技术鉴定化合物结构。结果从铁皮石斛中分离得到7个化合物,分别鉴定为:apigenin-6,8-di-C-β-D-glucopyranoside(Ⅰ),apigenin-6-C-α-L-arabinopyranosyl-8-C-β-D-xylopyranoside(Ⅱ),apigenin-6-C-(2″-O-β-D-glucopyranosyl)-α-L-arabinopyranoside(Ⅲ),apigenin-8-C-(2″-O-β-D-glucopyranosyl)-α-L-arabinopyranoside(Ⅳ),quercetin-3-O-β-D-rutinoside(Ⅴ),D-sucrose(Ⅵ),β-sitosterol-3-O-β-D-glucopyranoside(Ⅶ)。结论化合物Ⅰ~Ⅴ均为首次从该植物中分离得到。

Abstract

OBJECTIVE To study the chemical constituents of Dendrobium officinale. METHODS Various column chromatographic techniques were used to separate and purify the chemical constituents and their structures were elucidated by spectral analysis. RESULTS Seven compounds were isolated and identified as apigenin-6,8-di-C-β-D-glucopyranoside(I),apigenin-6-C-α-L-arabinopyranosyl-8-C-β-D-xylopyranoside(Ⅱ),apigenin-6-C-(2″-O-β-D-glucopyranosyl)-α-L-arabinopyranoside(Ⅲ),apigenin-8-C-(2″-O- β-D-glucopyranosyl)-α-L-arabinopyranoside(Ⅳ),quercetin-3-O-β-D-rutinoside(Ⅴ),D-sucrose(Ⅵ),and β-sitosterol-3-O-β-D-glucopyranoside(Ⅶ). CONCLUSION The compounds Ⅰ-Ⅴ were isolated from Dendrobium officinale Kimura et Migo for the first time.

关键词

石斛属 / 铁皮石斛 / apigenin-6 / 8-di-C-β-D-glucopyranoside / apigenin-6-C-α-L-arabinopyranosyl-8-C-β-D-xylopyranoside / Apigenin-6-C-(2″-O-β-D-glucopyranosyl)-α-L-arabinopyranoside

Key words

Dendrobium officinale Kimura et Migo / apigenin-6,8-di-C-β-D-glucopyranoside / apigenin-6-C-α-L-arabinopyranosyl-8-C-β-D-xylopyranoside / apigenin-6-C-(2″-O-β-D-glucopyranosyl)-α-L-arabinopyranoside

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罗镭,祝明,陈立钻,杨兵勋,邵喜英. 铁皮石斛化学成分的研究[J]. 中国药学杂志, 2013, 48(19): 1681-1683 https://doi.org/10.11669/cpj.2013.19.021
LUO Lei,ZHU Ming,CHEN Li-zuan,YANG Bing-xun ,SHAO Xi-ying. Chemical Constituents of Dendrobium officinale Kimura et Migo[J]. Chinese Pharmaceutical Journal, 2013, 48(19): 1681-1683 https://doi.org/10.11669/cpj.2013.19.021
中图分类号: R914   

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